Inter-set stretching for extra muscle growth? [Study review]

Categories: Articles, Training

I’m always looking for advanced training techniques to maximize muscle hypertrophy. Most have pros and cons and are only situationally effective, so I was excited to see there’s a new study by Evangelista et al. (2019) finding increased muscle growth with an inter-set stretching technique. Here’s my review of the study.


2 Groups of men were compared. The conventional group did a conventional full-body strength training program twice a week: 4 sets at 8-12RM with 90 seconds rest in between sets. The inter-set stretching group did – you’ll never guess – inter-set stretching in between sets. After each set, they performed a 30 second static stretch to their pain threshold. Nothing too hardcore but serious static stretching. See the programs and stretches below if you’re interested in the details.


Inter-set stretching program


Inter-set stretches


The following table shows the results after 8 weeks. Strength gains were similar between groups, but the inter-set stretching group gained more muscle across the board. The difference did not reach statistical significance between groups for any muscle, but the group-by-time interaction was significant for the vastus lateralis of the quads and the total sum of muscle thicknesses. This shows the total muscle growth rate occurred faster in the inter-set stretching group.


Inter-set stretching results


While these results are very promising, there are several reasons why I remain skeptical of the benefits of inter-set stretching.


First, static stretching has negative effects on performance. By making the nervous system more compliant and reducing muscle and tendon stiffness, static stretching can reduce muscle force production, activation, power output and consequently strength and total work output during training. Reduced performance can reduce long-term muscle growth. For example, in another study, 2 series of 25-second quad stretching during the warm-up significantly reduced muscle growth in a leg extension training program.

In the new study, repetitions were equated between groups. Assuming the static stretching reduced strength, that would mean the inter-set stretching group was training harder to complete the same workload, and that may be the reason they gained more muscle. The authors said the programs had progressive overload, but this is incompatible with equated reps between groups, a common problem in exercise science I’ve discussed before. For serious strength trainees that push for maximum progress, the stretching would hurt performance and they’d therefore achieve lower workloads, which would likely reduce rather than increase muscle growth.


Second, even if we assumed a direct effect of stretching, independent of performance, the stretching intensity used here would likely not suffice to stimulate muscle growth. In other research, far longer and more intensive stretching protocols have failed to stimulate muscle protein synthesis.


Third, even if the stretching intensity was sufficient to stimulate muscle growth, this may not work in trained individuals. The participants in the new study were untrained. This is not just a limitation for their motivation level but also physiologically. Muscle growth can occur in 2 ways: the muscle can lengthen from the addition of sarcomeres in series or the muscle can thicken from the addition of sarcomeres and whole myofibrils in parallel. Thickening is the primary growth mechanism in trained individuals, as a muscle can only lengthen so much. With full ROM training, you probably tap out the potential for substantial increases in muscle fascicle length quite soon. While muscle thickness and not length was measured, it’s possible that in the new study, much of the increased muscle size came from the addition of sarcomeres in series, as lengthening is a primary adaptation to overstretching. This would likely not be relevant for trained individuals already training each muscle with exercises imposing high tension at long muscle lengths during eccentric contractions.


In conclusion, this is a very promising study, but I generally don’t recommend inter-set static stretching yet.


Interested in more effective advanced training techniques to maximize muscle hypertrophy? I discuss which ones work and which don’t in my upcoming online PT Course.


Study reference

Interset Stretching vs. Traditional Strength Training: Effects on Muscle Strength and Size in Untrained Individuals. Evangelista et al. 2019. The Journal of Strength & Conditioning Research: January 24, 2019 – Volume Publish Ahead of Print – Issue – p. doi: 10.1519/JSC.0000000000003036


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About the author

Menno Henselmans

Formerly a business consultant, I've traded my company car to follow my passion in strength training. I'm now an online physique coach, scientist and international public speaker with the mission to help serious trainees master their physique.

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